Concept, hardware development, and clinical trials of a Galinstan based Mercury free sphygmomanometer: Merkfree

  • Pinto, F. J. et al. World Heart Day 2021: COVID-19, digital health, and tackling cardiovascular disease. Lancet 398(10310), 1467–1468 (2021).

    CAS 
    Article 

    Google Scholar
     

  • Muntner, P. et al. Measurement of blood pressure in humans: A scientific statement from the American Heart Association. Hypertension 73(5), e35–e66 (2019).

    CAS 
    Article 

    Google Scholar
     

  • Sharman, J. E. & Marwick, T. H. Accuracy of blood pressure monitoring devices: A critical need for improvement that could resolve discrepancy in hypertension guidelines. J. Hum. Hypertens. 33(2), 89–93 (2019).

    Article 

    Google Scholar
     

  • Campbell, N. R. & McKay, D. W. Accurate blood pressure measurement: why does it matter?. CMAJ 161(3), 277–278 (1999).

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Buchanan, S., Orris, P. & Karliner, J. Alternatives to the mercury sphygmomanometer. J. Public Health Policy. 32(1), 107–120 (2011).

    Article 

    Google Scholar
     

  • Murray, A. In praise of mercury sphygmomanometers. Appropriate sphygmomanometer should be selected. BMJ 322(7296), 1248–1249 (2001).

    CAS 
    Article 

    Google Scholar
     

  • Waugh, J. J., Gupta, M., Rushbrook, J., Halligan, A. & Shennan, A. H. Hidden errors of aneroid sphygmomanometers. Blood Press. Monit. 7(6), 309–312 (2002).

    Article 

    Google Scholar
     

  • McKay, D. W., Campbell, N. R., Parab, L. S., Chockalingam, A. & Fodor, J. G. Clinical assessment of blood pressure. J. Hum. Hypertens. 4(6), 639–645 (1990).

    CAS 
    PubMed 

    Google Scholar
     

  • van Montfrans, G. A. Oscillometric blood pressure measurement: progress and problems. Blood Press. Monit. 6(6), 287–290 (2001).

    Article 

    Google Scholar
     

  • Organization, W. H. WHO Technical Specifications for Automated Non-invasive Blood Pressure Measuring Devices with Cuff (World Health Organization, 2020).


    Google Scholar
     

  • Bailey, R. H., Knaus, V. L. & Bauer, J. H. Aneroid sphygmomanometers. An assessment of accuracy at a university hospital and clinics. Arch. Intern. Med. 151(7), 1409–1412 (1991).

    CAS 
    Article 

    Google Scholar
     

  • Jones, D. W., Frohlich, E. D., Grim, C. M., Grim, C. E. & Taubert, K. A. Mercury sphygmomanometers should not be abandoned: An advisory statement from the Council for High Blood Pressure Research. Am. Heart Assoc. Hypertens. 37(2), 185–186 (2001).

    CAS 

    Google Scholar
     

  • Kumar, R., Sahani, A. K. & Wander, G. S. A survey to gauge confidence of Indian clinicians on three primary devices for blood pressure measurement. Blood Press. Monit. 26(3), 196–199 (2021).

    Article 

    Google Scholar
     

  • Kaul, U. et al. Self-blood pressure measurement as compared to office blood pressure measurement in a large Indian population; the India Heart Study. J. Hypertens. 38(7), 1262–1270 (2020).

    CAS 
    Article 

    Google Scholar
     

  • “About us | Minamata Convention on Mercury.” https://www.mercuryconvention.org/en/about. Accessed 29 Sep 2021.

  • Tang, S. Y., Tabor, C., Kalantar-Zadeh, K. & Dickey, M. D. Gallium liquid metal: The devil’s elixir. Annu. Rev. Mater. Res. 51, 381–408. https://doi.org/10.1146/annurev-matsci-080819-125403 (2021).

    CAS 
    Article 

    Google Scholar
     

  • Liu, T., Sen, P. & Kim, C. J. Characterization of nontoxic liquid-metal alloy galinstan for applications in microdevices. J. Microelectromech. Syst. 21(2), 443–450. https://doi.org/10.1109/JMEMS.2011.2174421 (2012).

    CAS 
    Article 

    Google Scholar
     

  • Zhu, J. Y., Tang, S. Y., Khoshmanesh, K. & Ghorbani, K. An integrated liquid cooling system based on galinstan liquid metal droplets. ACS Appl. Mater. Interfaces. 8(3), 2173–2180. https://doi.org/10.1021/acsami.5b10769 (2016).

    CAS 
    Article 
    PubMed 

    Google Scholar
     

  • Zhang, C. et al. Nucleation and growth of polyaniline nanofibers onto liquid metal nanoparticles. Chem. Mater. 32(11), 4808–4819. https://doi.org/10.1021/acs.chemmater.0c01615 (2020).

    CAS 
    Article 

    Google Scholar
     

  • Ladd, C., So, J. H., Muth, J. & Dickey, M. D. 3D printing of free-standing liquid metal microstructures. Adv. Mater. 25(36), 5081–5085 (2013).

    CAS 
    Article 

    Google Scholar
     

  • Egry, I., Ricci, E., Novakovic, R. & Ozawa, S. Surface tension of liquid metals and alloys—Recent developments. Adv. Colloid Interface Sci. 159(2), 198–212 (2010).

    CAS 
    Article 

    Google Scholar
     

  • Doudrick, K. et al. Different shades of oxide: From nanoscale wetting mechanisms to contact printing of gallium-based liquid metals. Langmuir 30(23), 6867–6877 (2014).

    CAS 
    Article 

    Google Scholar
     

  • Kumar, R., Ghai, V. & Sahani, A. K. A surface modification approach to overcome wetting behavior of gallium-based liquid metal droplets. IEEE Trans. Nanotechnol. 21, 158–162 (2022).

    ADS 
    CAS 
    Article 

    Google Scholar
     

  • Khan, M. R., Eaker, C. B., Bowden, E. F. & Dickey, M. D. Giant and switchable surface activity of liquid metal via surface oxidation. Proc. Natl. Acad. Sci. U. S. A. 111(39), 14047–14051 (2014).

    ADS 
    CAS 
    Article 

    Google Scholar
     

  • Britannica, The Editors of Encyclopaedia. “Pascal’s principle”. Encyclopedia Britannica (2018). https://www.britannica.com/science/Pascals-principle. Accessed 26 Jan 2022.

  • Beevers, G., Lip, G. Y. & O’Brien, E. ABC of hypertension. Blood pressure measurement. Part I-sphygmomanometry: Factors common to all techniques. BMJ 322(7292), 981–985 (2001).

    CAS 
    Article 

    Google Scholar
     

  • Ulusoy, Ş, Özkan, G., Güvercin, B., Sökmen, Y. & Erdem, Y. Do physicians measure patients’ blood pressure, and are those measurements reliable?. J. Hum. Hypertens. 32(3), 203–211 (2018).

    Article 

    Google Scholar
     

  • Thavarajah, S., White, W. B. & Mansoor, G. A. Terminal digit bias in a specialty hypertension faculty practice. J. Hum. Hypertens. 17(12), 819–822 (2003).

    CAS 
    Article 

    Google Scholar
     

  • Executive Board. Public health impacts of exposure to mercury and mercury compounds: the role of WHO and ministries of public health in the implementation of the Minamata Convention (2014).